| Item Name | Description | Price | Location |
| Rare Candy | Increases Pokemon's level by 1 | - | |
| HP Up | Increases Pokemon's Max HP | 9800 | Celadon Dept. Store:5F |
| Protein | Increases Pokemon's Attack | 9800 | Celadon Dept. Store:5F |
| Iron | Increases Pokemon's Defense | 9800 | Celadon Dept. Store:5F |
| Carbos | Increases Pokemon's Speed | 9800 | Celadon Dept. Store:5F |
| Calcium | Increases Pokemon's Special | 9800 | Celadon Dept. Store:5F |
| PP Up | Increases Pokemon's PP Level | - | Various Areas |
| X Attack | Increases Pokemon's Attack(only in battle) | 550 | Celadon Dept. Store:5F |
| X Defend | Increases Pokemon's Defense(only in battle) | 550 | Celadon Dept. Store:5F |
| X Special | Increases Pokemon's Special(only in battle) | 350 | Celadon Dept. Store:5F |
| X Speed | Increases Pokemon's Speed(only in battle) | 350 | Celadon Dept. Store:5F |
| X Accuracy | Increases Pokemon's Accuracy(only in battle) | 950 | Celadon Dept. Store:5F |
| Guard Spec | Pokemon gains protection from Special attacks(only in battle) | 700 | Celadon Dept. Store:5F |
| Dire Hit | Raises Pokemon's attack efficiency | 650 | Celadon Dept. Store:5F |
| Item Name | Description | Price | Location |
| Nugget | Sells for 5000 | - | Various Areas |
| Gold Teeth | Give it to Walden for HM04 | - | Safari Park |
| S.S. Ticket | Boarding ticket for S.S. anne | - | Bill's Sea Cottage |
| PokeDoll | Give this to a girl in Saffron City. You can use them to escape from battle, as well | 1000 | Celadon Dept. Store |
| Silph Scope | Crucial for identifying ghosts in Pokemon Tower | - | Celadon City:Team Rocket HQ |
| Poke Flute | Wakes up sleeping Pokemon...in/out of the battle... | - | Lavender Town:Pokemon Tower |
| Old Rod | Used to fish up a Water Pokemon | - | Vermilion City |
| Good Rod | Can fish up that previous rod can't | - | |
| Super Rod | Can fish up that previous rod can't | - | Fuschia City |
| Itemfinder | Detects a hidden item that's near you | - |
| Exp. All | All Pokemon gets an EXP. Point | - |
| Coin | Use these at Game corner to play games or exchange for prizes | 1000 for 50 coins | Celadon City:Game corner |
| Coin Case | Save up to 9999 coins in this | - | Celadon City |
| Fresh Water | During Battle, it'll restore HP a little, or give it to soem thirsty person | 200 | Celadon Dept. Store |
| Soda Pop | During Battle, it'll restore HP a lot, or give it to soem thirsty person | 300 | Celadon Dept. Store |
| Lemonade | During Battle, it'll restore HP a lot more, or give it to soem thirsty person | 350 | Celadon Dept. Store |
| Item Name | Description | Price | Location |
| Fire Stone | Evolves: Vulpix, Glowlithe, Eevee | 2100 | Celadon City Dept Store...4F |
| Thunder Stone | Evolves: Pikachu, Eevee | 2100 | Celadon City Dept Store...4F |
| Water Stone | Evolves: Staru, Poliwhirl, Cloyster, Eevee | 2100 | Celadon City Dept Store...4F |
| Leaf Stone | Evolves: Exeggute, Weepinbell, Groom | 2100 | Celadon City Dept Store...4F |
| Moon Stone | Evolves: JigglyPuff, Clefairy, Nidorina, Nidorino | - | Various Areas |
| Helix Fossil | Take it to Pokemon Research Lab(Cinnabar Island) to resurrect it into Omanyte | - | Mt. Moon |
| Dome Fossil | Take it to Pokemon Research Lab(Cinnabar Island) to resurrect it into Kabuto | - | Mt. Moon |
| Old Amber | Take it to Pokemon Research Lab(Cinnabar Island) to resurrect it into Aerodactyl | - | Pewter City |
